Recommended positive controls: A549.
Predicted reactivity: Mouse (89%), Rat (88%), Rhesus Monkey (95%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EC 126.96.36.199; lysine tRNA ligase; Lysine--tRNA ligase; LysRS; Lysyl-tRNA synthetase
Gene Aliases: CMTRIB; DFNB89; KARS; KARS1; KARS2; KIAA0070; KRS
UniProt ID: (Human) Q15046
Entrez Gene ID: (Human) 3735