Product References
Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts.
American journal of respiratory cell and molecular biology
Bai L,Bernard K,Tang X,Hu M,Horowitz JC,Thannickal VJ,Sanders YY
Tue Jan 01 00:00:00 EST 2019
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Gene
Hu M,Liu L,Yao W
Sat Dec 15 00:00:00 EST 2018
Activation of p53 by costunolide blocks glutaminolysis and inhibits proliferation in human colorectal cancer cells.
Gene
Hu M,Liu L,Yao W
Sat Dec 15 00:00:00 EST 2018
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cell research
Cai WF,Zhang C,Wu YQ,Zhuang G,Ye Z,Zhang CS,Lin SC
Wed Aug 01 00:00:00 EDT 2018
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cell research
Cai WF,Zhang C,Wu YQ,Zhuang G,Ye Z,Zhang CS,Lin SC
Wed Aug 01 00:00:00 EDT 2018
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
American journal of respiratory cell and molecular biology
Ge J,Cui H,Xie N,Banerjee S,Guo S,Dubey S,Barnes S,Liu G
Thu Mar 01 00:00:00 EST 2018
Glutaminolysis Promotes Collagen Translation and Stability via α-Ketoglutarate-mediated mTOR Activation and Proline Hydroxylation.
American journal of respiratory cell and molecular biology
Ge J,Cui H,Xie N,Banerjee S,Guo S,Dubey S,Barnes S,Liu G
Thu Mar 01 00:00:00 EST 2018
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Nature communications
Wang YQ,Wang HL,Xu J,Tan J,Fu LN,Wang JL,Zou TH,Sun DF,Gao QY,Chen YX,Fang JY
Wed Feb 07 00:00:00 EST 2018
HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma.
Journal of cellular and molecular medicine
Li W,Chen C,Zhao X,Ye H,Zhao Y,Fu Z,Pan W,Zheng S,Wei L,Nong T,Li Z,Chen R
Wed Nov 01 00:00:00 EDT 2017
PPARδ Reprograms Glutamine Metabolism in Sorafenib-Resistant HCC.
Molecular cancer research : MCR
Kim MJ,Choi YK,Park SY,Jang SY,Lee JY,Ham HJ,Kim BG,Jeon HJ,Kim JH,Kim JG,Lee IK,Park KG
Fri Sep 01 00:00:00 EDT 2017
Glutaminolysis Was Induced by TGF-β1 through PP2Ac Regulated Raf-MEK-ERK Signaling in Endothelial Cells.
PloS one
Guo Y,Deng Y,Li X,Ning Y,Lin X,Guo S,Chen M,Han M
Fri Aug 11 00:00:00 EDT 2017
Aging Reduces an ERRalpha-Directed Mitochondrial Glutaminase Expression Suppressing Glutamine Anaplerosis and Osteogenic Differentiation of Mesenchymal Stem Cells.
Stem cells (Dayton, Ohio)
Huang T,Liu R,Fu X,Yao D,Yang M,Liu Q,Lu WW,Wu C,Guan M
Wed Feb 01 00:00:00 EST 2017
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.
Cell cycle (Georgetown, Tex.)
Pérez-Escuredo J,Dadhich RK,Dhup S,Cacace A,Van Hée VF,De Saedeleer CJ,Sboarina M,Rodriguez F,Fontenille MJ,Brisson L,Porporato PE,Sonveaux P
Thu Oct 13 00:00:00 EDT 2016
Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis.
The FEBS journal
Ha D,Bing SJ,Ahn G,Kim J,Cho J,Kim A,Herath KH,Yu HS,Jo SA,Cho IH,Jee Y
Thu Sep 01 00:00:00 EDT 2016
Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival.
Scientific reports
Fuchsberger T,Martínez-Bellver S,Giraldo E,Teruel-Martí V,Lloret A,Viña J
Fri Aug 12 00:00:00 EDT 2016
Aβ Induces Excitotoxicity Mediated by APC/C-Cdh1 Depletion That Can Be Prevented by Glutaminase Inhibition Promoting Neuronal Survival.
Scientific reports
Fuchsberger T,Martínez-Bellver S,Giraldo E,Teruel-Martí V,Lloret A,Viña J
Fri Aug 12 00:00:00 EDT 2016
CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.
RNA (New York, N.Y.)
Masamha CP,Xia Z,Peart N,Collum S,Li W,Wagner EJ,Shyu AB
Wed Jun 01 00:00:00 EDT 2016
Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells.
International journal of cancer
Kahlert UD,Cheng M,Koch K,Marchionni L,Fan X,Raabe EH,Maciaczyk J,Glunde K,Eberhart CG
Tue Mar 01 00:00:00 EST 2016
Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch.
Oncotarget
Lee SY,Jeon HM,Ju MK,Jeong EK,Kim CH,Park HG,Han SI,Kang HS
Tue Feb 16 00:00:00 EST 2016
A small subunit processome protein promotes cancer by altering translation.
Oncogene
Yang HW,Kim TM,Song SS,Menon L,Jiang X,Huang W,Black PM,Park PJ,Carroll RS,Johnson MD
Thu Aug 20 00:00:00 EDT 2015
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 EDT 2015
Increased glutamine catabolism mediates bone anabolism in response to WNT signaling.
The Journal of clinical investigation
Karner CM,Esen E,Okunade AL,Patterson BW,Long F
Sun Feb 01 00:00:00 EST 2015
The SIRT1/HIF2α axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy.
Cancer research
Corbet C,Draoui N,Polet F,Pinto A,Drozak X,Riant O,Feron O
Wed Oct 01 00:00:00 EDT 2014
A cell engineering strategy to enhance the safety of stem cell therapies.
Cell reports
Oricchio E,Papapetrou EP,Lafaille F,Ganat YM,Kriks S,Ortega-Molina A,Mark WH,Teruya-Feldstein J,Huse JT,Reuter V,Sadelain M,Studer L,Wendel HG
Thu Sep 25 00:00:00 EDT 2014
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression.
Nature
Masamha CP,Xia Z,Yang J,Albrecht TR,Li M,Shyu AB,Li W,Wagner EJ
Thu Jun 19 00:00:00 EDT 2014
Modulation of immune function by glutamatergic neurons in the cerebellar interposed nucleus via hypothalamic and sympathetic pathways.
Brain, behavior, and immunity
Xu FF,Huang Y,Wang XQ,Qiu YH,Peng YP
Thu May 01 00:00:00 EDT 2014
FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells.
The EMBO journal
Yeo H,Lyssiotis CA,Zhang Y,Ying H,Asara JM,Cantley LC,Paik JH
Wed Oct 02 00:00:00 EDT 2013
Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism.
Molecular autism
Shimmura C,Suzuki K,Iwata Y,Tsuchiya KJ,Ohno K,Matsuzaki H,Iwata K,Kameno Y,Takahashi T,Wakuda T,Nakamura K,Hashimoto K,Mori N
Tue Mar 26 00:00:00 EDT 2013
The NF-κB member p65 controls glutamine metabolism through miR-23a.
The international journal of biochemistry & cell biology
Rathore MG,Saumet A,Rossi JF,de Bettignies C,Tempé D,Lecellier CH,Villalba M
Sat Sep 01 00:00:00 EDT 2012
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC.
Proceedings of the National Academy of Sciences of the United States of America
Liu W,Le A,Hancock C,Lane AN,Dang CV,Fan TW,Phang JM
Tue Jun 05 00:00:00 EDT 2012
Systemic elevation of PTEN induces a tumor-suppressive metabolic state.
Cell
Garcia-Cao I,Song MS,Hobbs RM,Laurent G,Giorgi C,de Boer VC,Anastasiou D,Ito K,Sasaki AT,Rameh L,Carracedo A,Vander Heiden MG,Cantley LC,Pinton P,Haigis MC,Pandolfi PP
Fri Mar 30 00:00:00 EDT 2012
Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance.
Cancer biology & therapy
Ko YH,Lin Z,Flomenberg N,Pestell RG,Howell A,Sotgia F,Lisanti MP,Martinez-Outschoorn UE
Thu Dec 15 00:00:00 EST 2011
Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America
Colombo SL,Palacios-Callender M,Frakich N,De Leon J,Schmitt CA,Boorn L,Davis N,Moncada S
Tue Nov 02 00:00:00 EDT 2010
hydrolase
