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Proteintech
KGA/GAC Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
12855-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KGA/GAC Fusion Protein Ag3505 (370-669 aa encoded by BC038507)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize KGA and GAC.
Immunogen sequence: YVGFSNATF QSERESGDRN FAIGYYLKEK KCFPEGTDMV GILDFYFQLC SIEVTCESAS VMAATLANGG FCPITGERVL SPEAVRNTLS LMHSCGMYDF SGQFAFHVGL PAKSGVAGGI LLVVPNVMGM MCWSPPLDKM GNSVKGIHFC HDLVSLCNFH NYDNLRHFAK KLDPRREGGD QRVKSVINLL FAAYTGDVSA LRRFALSAMD MEQRDYDSRT ALHVAAAEGH VEVVKFLLEA CKVNPFPKDR WNNTPMDEAL HFGHHDVFKI LQEYQVQYTP QGDSDNGKEN QTVHKNLDGL L (370-669 aa encoded by BC038507)
Target Information
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glutaminase C; glutaminase, phosphate-activated; K-glutaminase; kidney-type glutaminase; L-glutamine amidohydrolase; pot. glutaminase (EC 3.5.1.2); putative; unnamed protein product
Gene Aliases: 6330442B14; AAD20; B230365M23Rik; CASGID; DEE71; EIEE71; GAC; GAM; GDPAG; GLS1; Glut; KGA; RATGLUT
UniProt ID: (Human) O94925, (Rat) P13264, (Mouse) D3Z7P3
Entrez Gene ID: (Human) 2744, (Rat) 24398, (Mouse) 14660
cellular amino acid metabolic process
glutamine metabolic process
glutamine catabolic process
protein homotetramerization
negative regulation of L-glutamine biosynthetic process
glutamate homeostasis
L-glutamate biosynthetic process
suckling behavior
regulation of respiratory gaseous exchange by neurological system process
chemical synaptic transmission
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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