Antibodies that detect KGA/GAC can be used in several scientific applications, including Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin) and Immunocytochemistry. This Rabbit polyclonal antibody targets KGA/GAC in Rat, Mouse and Human samples, and has been validated in experiments with 29 publications and 16 images featured in our data gallery.
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This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.
GLS; glutaminase C; Glutaminase kidney isoform, mitochondrial; Glutaminase kidney isoform, mitochondrial 65 kDa chain; Glutaminase kidney isoform, mitochondrial 68 kDa chain; glutaminase, phosphate-activated; K-glutaminase; L-glutamine amidohydrolase
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