Immunogen sequence: KRRNVPHEDI CEDSDIDGDY RVQNTSLEAI VQ
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Importin alpha Q1; Importin subunit alpha-3; importin subunit alpha-4; IPOA3; karyopherin alpha 4 (importin alpha 3); Karyopherin subunit alpha-4; MGC12217; MGC26703; QIP1; SRP3
Gene Aliases: IPOA3; KPNA4; QIP1; SRP3
UniProt ID: (Human) O00629
Entrez Gene ID: (Human) 3840
Molecular Function: transfer/carrier protein