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Invitrogen
Collagen II Monoclonal Antibody (2B1.5)
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.jpg?time=20240507?time=20240507 "Collagen II Antibody (MA5-12789) in ICC/IF")
.jpg?time=20240507?time=20240507 "Collagen II Antibody (MA5-12789) in ICC/IF")
.jpg?time=20240507?time=20240507 "Collagen II Antibody (MA5-12789) in IHC")
Product Details
MA5-12789
Applications
Tested Dilution
Publications
Product Specifications
Published species
Bovine,
Goat,
Guinea pig,
Human,
Mouse,
Pig,
Rabbit,
Rat,
Sheep
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2B1.5
Immunogen
A purified preparation of lathyritic type II collagen from embryonic chicken sternum
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
100 µg
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Staining of formalin/parafin tissues requires disgestion of tissue sections with pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.
Target Information
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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