Search
Invitrogen
LPL Monoclonal Antibody (5D2)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
MA5-18055
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Chicken,
Guinea pig,
Human,
Rat
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5D2
Immunogen
Purified bovine milk lipoprotein lipase protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody does not recognize hepatic lipase and does not react with mouse samples.
This target has a predicted molecular weight of 53 kDa.
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: adipose lipoprotein lipase; alpha lipase; lipopotein lipase precursor; Lipoprotein lipase; lipoprotein lipase (EC 3.1.1.34); lipoprotein lipase precursor; LPL; Phospholipase A1; triacylglycerol lipase; unnamed protein product
Gene Aliases: HDLCQ11; LIPD; LPL
UniProt ID: (Chicken) P11602, (Bovine) P11151, (Human) P06858, (Rat) Q06000, (Guinea pig) P11153
Entrez Gene ID: (Chicken) 396219, (Bovine) 280843, (Human) 4023, (Rat) 24539, (Guinea pig) 100135570
lipoprotein lipase activity
phospholipase activity
triglyceride lipase activity
receptor binding
calcium ion binding
heparin binding
phosphatidylcholine 1-acylhydrolase activity
lipase activity
apolipoprotein binding
protein homodimerization activity
heparan sulfate proteoglycan binding
phosphatidylserine 1-acylhydrolase activity
1-acyl-2-lysophosphatidylserine acylhydrolase activity
lipoprotein particle binding
protein binding
hydrolase activity
protein anchor
metal ion binding
carboxylic ester hydrolase activity
triglyceride binding
lipase
fatty acid metabolic process
fatty acid biosynthetic process
response to bacterium
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
lipid catabolic process
triglyceride catabolic process
cellular response to nutrient
chylomicron remodeling
very-low-density lipoprotein particle remodeling
cholesterol homeostasis
positive regulation of fat cell differentiation
positive regulation of inflammatory response
low-density lipoprotein particle mediated signaling
triglyceride homeostasis
cellular response to fatty acid
positive regulation of chemokine secretion
positive regulation of tumor necrosis factor secretion
triglyceride metabolic process
phospholipid metabolic process
response to glucose
retinoid metabolic process
lipid metabolic process
positive regulation of lipid storage
positive regulation of chemokine production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
high-density lipoprotein particle remodeling
very-low-density lipoprotein particle clearance
positive regulation of adipose tissue development
positive regulation of chemokine (C-X-C motif) ligand 2 production
response to cold
triglyceride biosynthetic process
response to drug
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support