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Invitrogen
LPL Monoclonal Antibody (5D2), Biotin
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Product Details
MA5-46591
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Hamster,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5D2
Immunogen
Purified bovine milk lipoprotein lipase protein
Conjugate
Form
Liquid
Concentration
Conc. not determined
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted molecular weight: 53 kDa.
Target Information
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha lipase; Lipoprotein lipase; lipoprotein lipase (EC 3.1.1.34); lipoprotein lipase precursor; LPL; O 1-4-5; Phospholipase A1; unnamed protein product
Gene Aliases: HDLCQ11; I79_006077; LIPD; LPL
UniProt ID: (Bovine) P11151, (Human) P06858, (Rat) Q06000, (Mouse) P11152
Entrez Gene ID: (Bovine) 280843, (Human) 4023, (Chinese hamster) 100689191, (Rat) 24539, (Mouse) 16956
lipoprotein lipase activity
phospholipase activity
triglyceride lipase activity
receptor binding
calcium ion binding
protein binding
heparin binding
phosphatidylcholine 1-acylhydrolase activity
apolipoprotein binding
protein homodimerization activity
heparan sulfate proteoglycan binding
phosphatidylserine 1-acylhydrolase activity
1-acyl-2-lysophosphatidylserine acylhydrolase activity
lipoprotein particle binding
lipase activity
hydrolase activity
protein anchor
metal ion binding
carboxylic ester hydrolase activity
triglyceride binding
lipase
fatty acid biosynthetic process
triglyceride metabolic process
phospholipid metabolic process
response to bacterium
response to glucose
positive regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol storage
positive regulation of sequestering of triglyceride
triglyceride catabolic process
cellular response to nutrient
chylomicron remodeling
very-low-density lipoprotein particle remodeling
cholesterol homeostasis
positive regulation of fat cell differentiation
positive regulation of inflammatory response
low-density lipoprotein particle mediated signaling
triglyceride homeostasis
cellular response to fatty acid
positive regulation of chemokine secretion
positive regulation of tumor necrosis factor secretion
retinoid metabolic process
lipid metabolic process
fatty acid metabolic process
positive regulation of lipid storage
lipid catabolic process
positive regulation of chemokine production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
high-density lipoprotein particle remodeling
very-low-density lipoprotein particle clearance
positive regulation of adipose tissue development
positive regulation of chemokine (C-X-C motif) ligand 2 production
response to cold
triglyceride biosynthetic process
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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