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Invitrogen
CLIC5 Monoclonal Antibody (CLIC5-02), PE
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FIGURE: 1 / 1
CLIC5 Antibody (MA5-28623) in Flow
Separation of CLIC5 transfected HEK-293 cells stained using anti-CLIC5 (CLIC5-02) PE Monoclonal antibody (Product # MA5-28623), concentration in sample 3 µg/mL (red-filled) from unstained CLIC5 transfected HEK-293 cells (GAM APC, black-dashed) in flow cytometry analysis (intracellular staining).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-28623
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
CLIC5-02
Immunogen
Human CLIC5a (amino acids 160-173)
Conjugate
PE
PE
PE
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Concentration
0.1 mg/mL
Amount
100 µg
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes CLIC5a, a 32 kDa intracellular protein which associates with proteins of actin complexes. Cross reactivity with CLIC5b was not determined.
Target Information
Clic5 encodes a protein that is required for normal hearing and is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti. Clic5 can insert into membranes and form poorly selective ion channels that may also transport chloride ions. Clic5 may play a role in the regulation of transepithelial ion absorption and secretion, and is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture. The Clic5 gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The protein encoded by Clic5 associates with actin-based cytoskeletal structures and may also play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for the Clic5 gene. Diseases associated with CLIC5 include Deafness, Autosomal Recessive 103 and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chloride intracellular channel protein 5; Glutaredoxin-like oxidoreductase CLIC5
Gene Aliases: CLIC5
Entrez Gene ID: (Human) 53405
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