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Invitrogen
Phospho-MARCKS (Ser167, Ser170) Recombinant Rabbit Monoclonal Antibody (MARCKSS167170-C9)
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FIGURE: 1 / 4
Phospho-MARCKS (Ser167, Ser170) Antibody (MA5-37189) in WB
Western blot analysis of Phospho-MARCKS (Ser167, Ser170) using NIH3T3 cell extract. Samples were untreated or treated with TPA, and incubated in monoclonal Phospho-MARCKS (Ser167, Ser170) antibody (Product # MA5-37189) with a dilution of 0.1 µg/mL.
Product Details
MA5-37189
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
MARCKSS167170-C9
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 0.10% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 80K protein; 80K-L protein; FLJ14368; FLJ90045; MARCKS; MARCS; Myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; protein kinase C substrate 80 kDa protein; Protein kinase C substrate, 80 kDa protein, light chain
Gene Aliases: 80K-L; KINC; MACS; MARCKS; PKCSL; PRKCSL
UniProt ID: (Human) P29966, (Mouse) P26645
Entrez Gene ID: (Human) 4082, (Rat) 25603, (Mouse) 17118
apoptotic process
mitochondrion organization
actin filament organization
central nervous system development
neural tube development
neurogenesis
response to endoplasmic reticulum stress
actin filament bundle assembly
actin crosslink formation
ventricular cardiac muscle tissue development
intracellular protein transport
brain development
positive regulation of neuron projection development
activation of phospholipase D activity
cell-substrate adhesion
positive regulation of dendritic spine morphogenesis
positive regulation of protein kinase C activity
positive regulation of glucose import in response to insulin stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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