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Phospho-MARCKS (Ser167, Ser170) Recombinant Rabbit Monoclonal Antibody (MARCKSS167170-C9), APC
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FIGURE: 1 / 1
Phospho-MARCKS (Ser167, Ser170) Antibody (MA5-37191) in Flow
Flow cytometry of Phospho-MARCKS (Ser167, Ser170) using C6 cells. Samples were incubated in monoclonal Phospho-MARCKS (Ser167, Ser170) antibody (Product # MA5-37191). Images correspond with the following conditions: unstained, negative control (blue), treated with staurosporine (red), with UV/TPA (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-37191
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
MARCKSS167170-C9
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser167/170 of human phospho MARCKS.
Conjugate
APC
APC
APC
Excitation/Emission Max
651/660 nm
View spectra
Form
Liquid
Purification
Protein A/G
Storage buffer
PBS with 0.20% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 80K protein; FLJ14368; FLJ90045; MARCS; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
Gene Aliases: 80K-L; KINC; MACS; PKCSL; PRKCSL
UniProt ID: (Human) P29966, (Mouse) P26645
Entrez Gene ID: (Human) 4082, (Mouse) 17118, (Rat) 25603
apoptotic process
mitochondrion organization
actin filament organization
central nervous system development
neural tube development
neurogenesis
response to endoplasmic reticulum stress
actin filament bundle assembly
actin crosslink formation
intracellular protein transport
regulation of cell shape
positive regulation of neuron projection development
cell-substrate adhesion
positive regulation of insulin receptor signaling pathway
positive regulation of dendritic spine morphogenesis
regulation of modification of postsynaptic actin cytoskeleton
ventricular cardiac muscle tissue development
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