|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MATK|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CHK; CSK homologous kinase; Csk-homologous kinase; Csk-type protein tyrosine kinase; Hematopoietic consensus tyrosine-lacking kinase; hydroxyaryl-protein kinase; HYL tyrosine kinase; leukocyte carboxyl-terminal src kinase related; Megakaryocyte-associated tyrosine-protein kinase; Protein kinase HYL; tyrosine kinase MATK; Tyrosine-protein kinase CTK; tyrosylprotein kinase
Gene Aliases: CHK; CTK; HHYLTK; HYL; HYLTK; Lsk; MATK
UniProt ID: (Human) P42679
Entrez Gene ID: (Human) 4145
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