Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: PYFEGLRKHY LLPAIEYFNG GPPAETDFGG DYGGTQYSLV VFNTVDCAPE SYVQCHAPTS SAYEFVTWLD GIKFMGGGGE SCSLIAEGLS TALQLFDDFK KMREQIGQTH RVCLLICNSP PYLLPAVEST TYSGCTTENL VQQIGERGIH FSIVSPRKLP ALRLLFEKAA P
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
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Protein Aliases: Activator interaction domain-containing protein 1; Activator-recruited cofactor 92 kDa component; ARC/mediator transcriptional coactivator subunit; ARC92; DKFZp434K0512; Mediator complex subunit 25; Mediator of RNA polymerase II transcription subunit 25; mediator of RNA polymerase II transcription, subunit 25 homolog; mediator of RNA polymerase II transcription, subunit 9 homolog; MGC70671; mMED25; p78; prostate-derived protein 78 kDa
Gene Aliases: 2610034E13Rik; 2610529E18Rik; ACID1; ARC92; BVSYS; CMT2B2; ESTM2; MED25; P78; PTOV2; RGD1305137; TCBAP0758
UniProt ID: (Human) Q71SY5, (Mouse) Q8VCB2
Entrez Gene ID: (Human) 81857, (Mouse) 75613, (Rat) 292889
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