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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein encompassing a sequence within the center region of human NEIL1. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 20% glycerol |
Contains |
0.025% ProClin 300 |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2792731 |
Keep as concentrated solution.
Predicted reactivity: Mouse (87%), Rat (87%), Bovine (91%).
Positive Control: 293T, 293T nuclear extract, NEIL1-transfected 293T.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA endonuclease eight-like glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; Endonuclease 8-like 1; endonuclease VIII; Endonuclease VIII-like 1; FLJ22402; FPG1; NEH1; nei endonuclease VIII-like 1; Nei homolog 1; nei-like DNA glycosylase 1; Nei-like protein 1
Gene Aliases: FPG1; hFPG1; NEI1; NEIL1
UniProt ID: (Human) Q96FI4
Entrez Gene ID: (Human) 79661
Molecular Function:
DNA glycosylase
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