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Bethyl Laboratories
OBFC2A Polyclonal Antibody
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FIGURE: 1 / 1
OBFC2A Antibody (A302-255A) in IP
Detection of human OBFC2A by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-OBFC2A antibody (Product # A302-255A) used for IP at 10 µg/mg lysate. OBFC2A was also immunoprecipitated by rabbit anti-OBFC2A antibody A302-254A, which recognizes an upstream epitope. For blotting immunoprecipitated OBFC2A, A302-255A was used at 1 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A302-255A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 150 to 200 of human oligonucleotide/oligosaccharide-binding fold containing 2A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
NABP1, also known as NABP1/Ssb2, is a single-stranded DNA-binding protein involved in genome maintenance and stability. The gene encoding NABP1 is regulated by RORgamma2, a retinoid-related orphan receptor critical for thymopoiesis. Research has demonstrated that NABP1 plays a compensatory role in thymic maturation, particularly in conditions where its homolog, SSB1, is knocked out. Despite SSB1's vital role in neonatal survival, NABP1 remains non-essential for thymic maturation and male fertility, indicating partial functional redundancy between these proteins. Furthermore, studies on the C-terminal regions of NABP1 have shown distinct roles in nucleic acid binding, contributing to DNA and RNA metabolism. These findings highlight NABP1's importance in genomic integrity and its complex interplay within cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hSSB2; lncRNA AK130181; NABP1 3'UTR overlapping transcript 1; Nucleic acid-binding protein 1; oligonucleotide/oligosaccharide-binding fold containing 2A; Oligonucleotide/oligosaccharide-binding fold-containing protein 2A; Sensor of single-strand DNA complex subunit B2; Sensor of ssDNA subunit B2; Single-stranded DNA-binding protein 2; SOSS complex subunit B2; SOSS-B2; unnamed protein product
Gene Aliases: NABP1; NABP1-OT1; OBFC2A; SOSS-B2; SSB2
UniProt ID: (Human) Q96AH0
Entrez Gene ID: (Human) 64859
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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