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          • Primary Antibodies ›
          • TAS2R41 Antibodies

          Osenses

          TAS2R41 Polyclonal Antibody

          2 References
          View all (8) TAS2R41 antibodies

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          Cite TAS2R41 Polyclonal Antibody

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          TAS2R41 Polyclonal Antibody

          Product Details

          OSR00165W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from aa region 200-250 of human TAS2R41 conjugated to blue carrier protein was used as the antigen
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: TAS2R41.

          Target Information

          TAS2R41 is a receptor that may play a role in the perception of bitterness and belongs to the G-protein receptor superfamily. TAS2R41 is expressed mainly in taste receptor cells of the tongue and the palate eptithelia. Structurally, the TAS2R41 gene encodes a seven trans-membrane receptor protein and is clustered together with eight other taste receptor genes on chromosome 7. The compound chloramphenicol is an agonist for the TAS2R41 protein. Further, TAS2R41 may play a role in sensing the chemical composition of the gastrointestinal content. The activity of TAS2R41 may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2R41 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: MGC119928; MGC119929; T2R41; T2R59; Taste receptor type 2 member 41; Taste receptor type 2 member 59; taste receptor, type 2, member 41

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          Gene Aliases: T2R41; T2R59; TAS2R41

          View more View less

          UniProt ID: (Human) P59536

          View more View less

          Entrez Gene ID: (Human) 259287

          View more View less

          Function(s)
          G-protein coupled receptor activity protein binding bitter taste receptor activity
          Process(es)
          detection of chemical stimulus involved in sensory perception of bitter taste signal transduction G-protein coupled receptor signaling pathway sensory perception of taste
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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