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Invitrogen
WRCH1 Polyclonal Antibody
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Product Details
PA5-51270
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide of human RHOU
Conjugate
Form
Liquid
Concentration
2.1 mg/mL
Amount
210 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total RHOU protein.
Target Information
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310026M05Rik; CDC42-like GTPase 1; GTP-binding protein like 1; GTP-binding protein SB128; GTP-binding protein-like 1; ras homolog gene family, member U; ras-like gene family member U; Rho family GTPase; Rho GTPase-like protein ARHU; Rho-related GTP-binding protein RhoU; Ryu GTPase; unnamed protein product; Wnt-1 responsive Cdc42 homolog 1; WRCH-1
Gene Aliases: ARHU; CDC42L1; G28K; hG28K; RHOU; SB128; WRCH1
UniProt ID: (Human) Q7L0Q8
Entrez Gene ID: (Human) 58480
G1/S transition of mitotic cell cycle
endocytosis
cytoskeleton organization
actin filament organization
signal transduction
small GTPase mediated signal transduction
regulation of cell shape
Rac protein signal transduction
establishment of cell polarity
actin cytoskeleton organization
regulation of small GTPase mediated signal transduction
positive regulation of focal adhesion disassembly
positive regulation of protein targeting to mitochondrion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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