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Proteintech
PDE4A Polyclonal Antibody
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Product Details
16226-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDE4A Fusion Protein Ag8018 (297-647 aa encoded by BC019864)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVIDMVLAT DMSKHMTLLA DLKTMVETKK VTSSGVLLLD NYSDRIQVLR NMVHCADLSN PTKPLELYRQ WTDRIMAEFF QQGDRERERG MEISPMCDKH TASVEKSQVG FIDYIVHPLW ETWADLVHPD AQEILDTLED NRDWYYSAIR QSPSPPPEEE SRGPGHPPLP DKFQFELTLE EEEEEEISMA QIPCTAQEAL TAQGLSGVEE ALDATIAWEA SPAQESLEVM AQEASLEAEL EAVYLTQQAQ STGSAPVAPD EFSSREEFVV AVSHSSPSAL ALQSPLLPAW RTLSVSEHAP GLPGLPSTAA EVEAQREHQA AKRACSACAG TFGEDTSALP APGGGGSGGD PT (297-647 aa encoded by BC019864)
Target Information
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3',5'-cyclic-AMP phosphodiesterase 4A; cAMP-specific 3',5'-cyclic phosphodiesterase 4A; cAMP-specific phosphodiesterase 4A; cAMP-specific phosphodiesterase PDE4A; cyclic AMP (cAMP)-specific phosphodiesterase; cyclic AMP specific phosphodiesterase family 4 sub-family A isoform 11; cyclic AMP specific phosphodiesterase PDE4A5A; DPDE2; dunce; PDE46; phosphodiesterase 4A, cAMP specific; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila); phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4; type-IVA cyclic AMP specific phosphodiesterase HPDE4A
Gene Aliases: D9Ertd60e; DPDE2; PDE4; PDE46; PDE4A; PHOSA
UniProt ID: (Human) P27815, (Mouse) O89084, (Rat) P54748
Entrez Gene ID: (Human) 5141, (Mouse) 18577, (Rat) 25638
cAMP catabolic process
signal transduction
G-protein coupled receptor signaling pathway
sensory perception of smell
cellular response to xenobiotic stimulus
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
regulation of cAMP/PKA signal transduction
negative regulation of cAMP/PKA signal transduction
regulation of protein kinase A signaling
cellular response to drug
regulation of cAMP-mediated signaling
metabolic process
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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