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Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE.
cAMP-specific 3',5'-cyclic phosphodiesterase 4A; cAMP-specific phosphodiesterase PDE4A; cyclic AMP specific phosphodiesterase PDE4A5A; cyclic AMP-specific phosphodiesterase OCPDE4A1A; D9Ertd60e; DPDE2; dunce; LOC100009247; PDE4; PDE46; Pde4a; PHOSA; phosphodiesterase 4A; phosphodiesterase 4A, cAMP specific; phosphodiesterase 4A, cAMP-specific; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila); phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4
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