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Invitrogen
PDE4A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-31130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide specific only for PDE4A8 protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris glycine, pH 7.4-7.9, with 30% glycerol, 0.5% BSA
Contains
0.02% Sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-31130 detects PDE4A8 from rat, mouse samples.
Target Information
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cAMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4A; cAMP-specific phosphodiesterase 4A; cAMP-specific phosphodiesterase PDE4A; cyclic AMP (cAMP)-specific phosphodiesterase; cyclic AMP specific phosphodiesterase family 4 sub-family A isoform 11; cyclic AMP specific phosphodiesterase PDE4A5A; cyclic nucleotide phosphodiesterase; dunce; long form PDE4A; PDE4A10 cAMP phosphodiesterase; phosphodiesterase 4A, cAMP specific; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila); phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4; similar to Pde4a1; type-IVA cyclic AMP specific phosphodiesterase HPDE4A; unnamed protein product
Gene Aliases: D9Ertd60e; DPDE2; PDE4; PDE46; PHOSA
UniProt ID: (Human) P27815, (Mouse) O89084, (Rat) P54748
Entrez Gene ID: (Human) 5141, (Mouse) 18577, (Rat) 25638
cAMP catabolic process
signal transduction
sensory perception of smell
modulation of synaptic transmission
cellular response to xenobiotic stimulus
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
regulation of cAMP/PKA signal transduction
negative regulation of cAMP/PKA signal transduction
G-protein coupled receptor signaling pathway
response to xenobiotic stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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