|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from near N-terminus of human PDE7B.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human (100%) Gibbon, Monkey (94%) Gorilla, Mouse, Rat, Elephant, Horse, Rabbit (88%) Opossum (82%).
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5'-cyclic phosphodiesterase; 5'-cyclic phosphodiesterase 7B; bA472E5.1; cAMP-specific 3'; cAMP-specific 3',5'-cyclic phosphodiesterase 7B; high-affinity cAMP-specific 3'; high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase; rolipram-insensitive phosphodiesterase type 7
Gene Aliases: bA472E5.1; PDE7B
UniProt ID: (Human) Q9NP56
Entrez Gene ID: (Human) 27115
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