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The PDHX gene encodes component X of the pyruvate dehydrogenase (PDH) complex. For a detailed description of the pyruvate dehydrogenase complex. The mammalian PDH complex differs from that in E. coli and from the other mammalian alpha-keto acid dehydrogenases by the presence of a 53-kDa protein called protein X. Component X binds to the E3 component of the PDH complex (Robinson et al., 1990 ; Aral et al., 1997 ).
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Protein Aliases: component X; Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex; dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (E3-binding protein) (proX); E3-binding protein; E3BP; IPF1; lipoyl-containin; Lipoyl-containing pyruvate dehydrogenase complex component X; proX; pyruvate dehydrogenase; pyruvate dehydrogenase complex, component X; pyruvate dehydrogenase complex, E3-binding protein subunit; pyruvate dehydrogenase complex, lipoyl-containing component X; Pyruvate dehydrogenase protein X component, mitochondrial
Gene Aliases: Ac1164; AI481367; DLDBP; E3BP; OPDX; PDHX; PDX1; proX
UniProt ID: (Human) O00330, (Mouse) Q8BKZ9
Entrez Gene ID: (Human) 8050, (Rat) 311254, (Mouse) 27402
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