This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: YIAVSLLPHE TLLEIENAVE SGRALLPILQ WHKHPNDYFS KEASKLYFNS LRTYWQELID LNTGESTDID VKEALINAFK RLDNDISLEA QVGDPNSFLN YLVLRVAFSG ATACVAHVD
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; PDP; PDP 1; PDPC 1; PPM2C; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 1; pyruvate dehydrogenase phosphatase isoenzyme 2; pyruvate dehydrogenase phosphatase, catalytic subunit 1
Gene Aliases: Gm1024; PDH; PDP; PDP1; PDPC; PPM2A; PPM2C