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Product Details
PA5-115773
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PLXND1(Accession Q9Y4D7), corresponding to amino acid residues W722-L772.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900408
Product Specific Information
Antibody detects endogenous levels of total Plexin D1.
Target Information
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC75353; Plexin-D1
Gene Aliases: KIAA0620; PLEXD1; PLXND1
UniProt ID: (Human) Q9Y4D7
Entrez Gene ID: (Human) 23129
angiogenesis
patterning of blood vessels
outflow tract morphogenesis
cardiac septum development
synapse assembly
branchiomotor neuron axon guidance
regulation of cell migration
positive regulation of protein binding
aorta development
endothelial cell migration
regulation of angiogenesis
regulation of axon extension involved in axon guidance
dichotomous subdivision of terminal units involved in salivary gland branching
coronary vasculature development
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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