POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Protein Aliases: DNA polymerase epsilon p12 subunit; DNA polymerase epsilon subunit 4; DNA polymerase epsilon subunit p12; DNA polymerase II subunit 4; polymerase (DNA) epsilon 4, accessory subunit; polymerase (DNA-directed), epsilon 4 (p12 subunit); polymerase (DNA-directed), epsilon 4, accessory subunit
Gene Aliases: 2400007P05Rik; 5830430F06Rik; p12; POLE4; YHHQ1
Molecular Function: DNA-binding transcription factor