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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunocytochemistry (ICC/IF) |
10 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
RABGAP1 (NP_036329.2, 1 a.a. approximately 997 a.a) full-length human protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
See Label |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4 |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Sequence of this protein is as follows: MDDQPGEKEL VKRSQLDGEG DGPLSNQLSA SSTINPVPLV GLQKPEMSLP VKPGQGDSEA SSPFTPVADE DSVVFSKLTY LGCASVNAPR SEVEALRMMS ILRSQCQISL DVTLSVPNVS EGIVRLLDPQ TNTEIANYPI YKILFCVRGH DGTPESDCFA FTESHYNAEL FRIHVFRCEI QEAVSRILYS FATAFRRSAK QTPLSATAAP QTPDSDIFTF SVSLEIKEDD GKGYFSAVPK DKDRQCFKLR QGIDKKIVIY VQQTTNKELA IERCFGLLLS PGKDVRNSDM HLLDLESMGK SSDGKSYVIT GSWNPKSPHF QVVNEETPKD KVLFMTTAVD LVITEVQEPV RFLLETKVRV CSPNERLFWP FSKRSTTENF FLKLKQIKQR ERKNNTDTLY EVVCLESESE RERRKTTASP SVRLPQSGSQ SSVIPSPPED DEEEDNDEPL LSGSGDVSKE CAEKILETWG ELLSKWHLNL NVRPKQLSSL VRNGVPEALR GEVWQLLAGC HNNDHLVEKY RILITKESPQ DSAITRDINR TFPAHDYFKD TGGDGQDSLY KICKAYSVYD EEIGYCQGQS FLAAVLLLHM PEEQAFSVLV KIMFDYGLRE LFKQNFEDLH CKFYQLERLM QEYIPDLYNH FLDISLEAHM YASQWFLTLF TAKFPLYMVF HIIDLLLCEG ISVIFNVALG LLKTSKDDLL LTDFEGALKF FRVQLPKRYR SEENAKKLME LACNMKISQK KLKKYEKEYH TMREQQAQQE DPIERFEREN RRLQEANMRL EQENDDLAHE LVTSKIALRK DLDNAEEKAD ALNKELLMTK QKLIDAEEEK RRLEEESAQL KEMCRRELDK AESEIKKNSS IIGDYKQICS QLSERLEKQQ TANKVEIEKI RQKVDDCERC REFFNKEGRV KGISSTKEVL DEDTDEEKET LKNQLREMEL ELAQTKLQLV EAECKIQDLE HHLGLALNEV QAAKKTWFNR TLSSIKTATG VQGKETC
RABGAP1 may act as a GTPase-activating protein of RAB6A and play a role in microtubule nucleation by centrosome. It may participate in a RAB6A-mediated pathway involved in the metaphase-anaphase transition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GAP and centrosome-associated protein; Rab GTPase-activating protein 1; rab6 GTPase activating protein (GAP and centrosome-associated); Rab6 GTPase activating protein, GAPCenA; Rab6 GTPase-activating protein GAPCenA; RP11-123N4.2; TBC1 domain family, member 11
Gene Aliases: GAPCENA; HSPC094; RABGAP1; TBC1D11
UniProt ID: (Human) Q9Y3P9
Entrez Gene ID: (Human) 23637
Molecular Function:
G-protein modulator
protein-binding activity modulator
GTPase-activating protein
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