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Proteintech
SETDB2 Polyclonal Antibody
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Product Details
14428-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SETDB2 Fusion Protein Ag5795 (353-707 aa encoded by BC047434)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PQVRLQVFK TEQKGWGVRC LDDIDRGTFV CIYSGRLLSR ANTEKSYGID ENGRDENTMK NIFSKKRKLE VACSDCEVEV LPLGLETHPR TAKTEKCPPK FSNNPKELTM ETKYDNISRI QYHSVIRDPE SKTAIFQHNG KKMEFVSSES VTPEDNDGFK PPREHLNSKT KGAQKDSSSN HVDEFEDNLL IESDVIDITK YREETPPRSR CNQATTLDNQ NIKKAIEVQI QKPQEGRSTA CQRQQVFCDE ELLSETKNTS SDSLTKFNKG NVFLLDATKE GNVGRFLNHS CCPNLLVQNV FVETHNRNFP LVAFFTNRYV KARTELTWDY GYEAGTVPEK EIFCQCGVNK CRKKIL (353-707 aa encoded by BC047434)
Target Information
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bifurcated 2; Chronic lymphocytic leukemia deletion region gene 8 protein; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Histone-lysine N-methyltransferase SETDB2; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2
Gene Aliases: C13orf4; CLLD8; CLLL8; KMT1F; SETDB2
UniProt ID: (Human) Q96T68
Entrez Gene ID: (Human) 83852
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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