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Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).
bifurcated 2; C13orf4; Chronic lymphocytic leukemia deletion region gene 8 protein; Clld8; CLLL8; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Gm293; Histone-lysine N-methyltransferase SETDB2; KMT1F; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2; SET domain, bifurcated 2; Setdb2; Setdb2-Phf11-1-Phf11-2 fusion
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