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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SETDB2 Antibodies

          Invitrogen

          SETDB2 Polyclonal Antibody

          View all (16) SETDB2 antibodies

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          Cite SETDB2 Polyclonal Antibody

          • Antibody Testing Data (1)
          SETDB2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          SETDB2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SETDB2 Antibody (PA5-18112) in WB

          Western blot analysis of SETDB2 using SETDB2 Polyclonal Antibody (Product # PA5-18112) (0.3 µg/mL) in staining of Nuclear HeLa lysate (35 µg protein in RIPA buffer). Detected by chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SETDB2 Antibody in Western Blot (WB)
          SETDB2 Polyclonal Antibody

          Product Details

          PA5-18112

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-3 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (GEKNGDAKTFWME) corresponding to the N-terminus amino acids of SETDB2 (aa 2-15).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10980542

          Product Specific Information

          This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 1,000.

          Target Information

          Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: bifurcated 2; Chronic lymphocytic leukemia deletion region gene 8 protein; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Histone-lysine N-methyltransferase SETDB2; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2

          View more View less

          Gene Aliases: C13orf4; CLLD8; CLLL8; KMT1F; SETDB2

          View more View less

          UniProt ID: (Human) Q96T68

          View more View less

          Entrez Gene ID: (Human) 83852

          View more View less

          Function(s)
          DNA binding protein binding zinc ion binding histone-lysine N-methyltransferase activity histone methyltransferase activity (H3-K9 specific) histone modifying enzyme
          Process(es)
          heart looping chromosome segregation mitotic nuclear division negative regulation of transcription, DNA-templated cell division histone H3-K9 methylation left/right axis specification
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

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