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Product Details
12699-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SGK3 Fusion Protein Ag3149 (160-496 aa encoded by BC015326)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TDFDFLKVI GKGSFGKVLL AKRKLDGKFY AVKVLQKKIV LNRKEQKHIM AERNVLLKNV KHPFLVGLHY SFQTTEKLYF VLDFVNGGEL FFHLQRERSF PEHRARFYAA EIASALGYLH SIKIVYRDLK PENILLDSVG HVVLTDFGLC KEGIAISDTT TTFCGTPEYL APEVIRKQPY DNTVDWWCLG AVLYEMLYGL PPFYCRDVAE MYDNILHKPL SLRPGVSLTA WSILEELLEK DRQNRLGAKE DFLEIQNHPF FESLSWADLV QKKIPPPFNP NVAGPDDIRN FDTAFTEETV PYSVCVSSDY SIVNASVLEA DDAFVGFSYA PPSEDLFL (160-496 aa encoded by BC015326)
Target Information
SGKL (SGK3) is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cytokine-independent survival kinase; DKFZp781N0293; Serine/threonine-protein kinase Sgk3; serum/glucocorticoid regulated kinase 3; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like
Gene Aliases: 2510015P22Rik; A330005P07Rik; CISK; fy; fz; SGK2; SGK3; SGKL
UniProt ID: (Human) Q96BR1, (Mouse) Q9ERE3
Entrez Gene ID: (Human) 23678, (Mouse) 170755, (Rat) 171498
protein kinase activity
protein serine/threonine kinase activity
calcium channel regulator activity
protein binding
ATP binding
potassium channel regulator activity
sodium channel regulator activity
chloride channel regulator activity
phosphatidylinositol binding
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
regulation of cell growth
protein phosphorylation
cellular sodium ion homeostasis
response to stress
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
regulation of cell migration
positive regulation of transporter activity
ion transmembrane transport
intracellular signal transduction
regulation of cell proliferation
regulation of apoptotic process
regulation of sequence-specific DNA binding transcription factor activity
phosphorylation
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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