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SGKL (SGK3) is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
2510015P22Rik; A330005P07Rik; CISK; cytokine-independent survival kinase; DKFZp781N0293; fy; fz; Serine/threonine-protein kinase Sgk3; serum glucocorticoid regulated kinase 3; serum/glucocorticoid regulated kinase 3; serum/glucocorticoid regulated kinase family member 3; serum/glucocorticoid regulated kinase family, member 3; serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like; SGK2; SGK3; Sgkl
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