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Product Details
PA5-33021
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 20 amino acid peptide from N-terminus of human SGK3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550482
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Horse, Rabbit (95%); Elephant, Panda, Opossum, Turkey, Chicken (90%); Platypus, Lizard, Pufferfish, Zebrafish (85%); Xenopus (80%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
SGKL (SGK3) is a serine/threonine protein kinase which is similar to serum- and glucocorticoid-induced protein kinase (SGK). Unlike SGK, SGKL is not induced by serum or glucocorticoids. It is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytokine-independent survival kinase; DKFZp781N0293; Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like
Gene Aliases: CISK; SGK2; SGK3; SGKL
UniProt ID: (Human) Q96BR1
Entrez Gene ID: (Human) 23678
protein kinase activity
protein serine/threonine kinase activity
calcium channel regulator activity
protein binding
ATP binding
potassium channel regulator activity
sodium channel regulator activity
chloride channel regulator activity
phosphatidylinositol binding
non-receptor serine/threonine protein kinase
regulation of cell growth
protein phosphorylation
cellular sodium ion homeostasis
response to stress
positive regulation of sodium ion transport
peptidyl-serine phosphorylation
regulation of cell migration
positive regulation of transporter activity
ion transmembrane transport
intracellular signal transduction
regulation of cell proliferation
regulation of apoptotic process
regulation of sequence-specific DNA binding transcription factor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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