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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: TGNSSKTQGE LFLLLDSRGA FHTKGYYAAV EAKKERMSKH AQTFGAKQPT HQGGPAQDRG VYLSLLASLR TRAQLPVVV
Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a human homologue of yeast SKI2 and may be involved in antiviral activity by blocking translation of poly(A) deficient mRNAs. This gene is located in the class III region of the major histocompatibility complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Helicase-like protein; HLP; Ski2; Superkiller complex protein 2
Gene Aliases: DDX13; SKI2W; SKIC2; SKIV2; SKIV2L; W
Entrez Gene ID: (Human) 6499
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