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SLC40A1 Polyclonal Antibody
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Product Details
BS-4906R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Chicken,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SLC40A1/FPN1, amino acids 331-430.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAR1; Cell adhesion regulator; duodenal-specific; Ferroportin; ferroportin 1; ferroportin 1; ireg1; Ferroportin-1; FPN-N; iron regulated gene 1; Iron-regulated transporter 1; Metal transporter protein 1; metal transporting protein 1; MTP1; polycythaemia; SLC11A3 iron transporter; SLC40 iron transporter; SLC40A1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1; transporter; unnamed protein product
Gene Aliases: Dusg; FPN; FPN1; Fpt1; HFE4; IREG1; MST079; MSTP079; MTP; MTP1; Ol5; Pcm; SLC11A3; Slc39a1; SLC40A1
UniProt ID: (Human) Q9NP59, (Mouse) Q9JHI9, (Rat) Q923U9
Entrez Gene ID: (Human) 30061, (Chicken) 423984, (Mouse) 53945, (Rat) 170840
lymphocyte homeostasis
endothelium development
transcription from RNA polymerase II promoter
ion transport
iron ion transport
cellular iron ion homeostasis
apoptotic process
iron ion transmembrane transport
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
spleen development
establishment of localization in cell
transmembrane transport
spleen trabecula formation
multicellular organismal iron ion homeostasis
ferrous iron export
transport
regulation of transcription from RNA polymerase II promoter in response to iron
iron ion homeostasis
ferrous iron transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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