SLC40A1 is an iron-regulated transporter assumed to play roles in intestinal iron absorption and cellular iron release. It mediates iron efflux in the presence of ferroxidase. Defects in SLC40A1 cause hemochromatosis type 4 (HFE4), which is an autosomal dominant iron-loading disorder.
CAR1; Cell adhesion regulator; duodenal-specific; Ferroportin; ferroportin 1; Ferroportin-1; iron regulated gene 1; Iron-regulated transporter 1; Metal transporter protein 1; metal transporting protein 1; MTP1; polycythaemia; SLC11A3 iron transporter; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1; Solute carrier family 40 member 1
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