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Proteintech
SPACA1 Polyclonal Antibody
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Product Details
12829-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SPACA1 Fusion Protein Ag3549 (26-229 aa encoded by BC029488)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SARGTNVTA AVQDAGLAHE GEGEEETENN DSETAENYAP PETEDVSNRN VVKEVEFGMC TVTCGIGVRE VILTNGCPGG ESKCVVRVEE CRGPTDCGWG KPISESLESV RLACIHTSPL NRFKYMWKLL RQDQQSIILV NDSAILEVRK ESHPLAFECD TLDNNEIVAT IKFTVYTSSE LQMRRSSLPA TDAALIFVLT IGVII (26-229 aa encoded by B C029488)
Target Information
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Sperm acrosomal membrane-associated protein 32; Sperm acrosome membrane-associated protein 1
Gene Aliases: 1700124L11Rik; 4930540L03Rik; RGD1560284; SAMP32; SPACA1
UniProt ID: (Human) Q9HBV2, (Mouse) Q9DA48
Entrez Gene ID: (Human) 81833, (Rat) 500432, (Mouse) 67652
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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