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Proteintech
TAF3 Polyclonal Antibody
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Product Details
18901-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TAF3 Fusion Protein Ag13536 (443-721 aa encoded by BC024661)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TKSGSTPLP LSGGTSSSDN SWTMDASIDE VVRKAKLGTP SNMPPNFPYI SSPSVSPPTP EPLHKVYEEK TKLPSSVEVK KKLKKELKTK MKKKEKQRDR EREKDKNKDK SKEKDKVKEK EKDKETGRET KYPWKEFLKE EEADPYKFKI KEFEDVDPKV KLKDGLVRKE KEKHKDKKKD REKGKKDKDK REKEKVKDKG REDKMKAPAP PLVLPPKELA LPLFSPATAS RVPAMLPSLL PVLPEKLFEE KEKVKEKEKK KDKKEKKKKK EKEKEKKEK (443-721 aa encoded by BC024661)
Target Information
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process. Belongs to the TFIID complex which is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TAF10 via the histone fold. Interacts with TAF13, TBP, SAP130 and GCN5L2. Interacts with TBPL2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 140 kDa TATA box-binding protein-associated factor; MGC25063; RNA polymerase II transcription factor TAFII140; TAF(II)140; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; Transcription initiation factor TFIID subunit 3
Gene Aliases: TAF140; TAF3; TAFII-140; TAFII140
UniProt ID: (Human) Q5VWG9
Entrez Gene ID: (Human) 83860
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
transcription from RNA polymerase II promoter
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
maintenance of protein location in nucleus
positive regulation of transcription initiation from RNA polymerase II promoter
negative regulation of signal transduction by p53 class mediator
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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