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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | View 3 publications 3 publications |
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
1:50-1:500 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 14 publications 14 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Miscellaneous PubMed (Misc) |
- | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
TBR1 Fusion Protein Ag14935 (1-196 aa encoded by BC104844) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.27 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MQLEHCLSP SIMLSKKFLN VSSSYPHSGG SELVLHDHPI ISTTDNLERS SPLKKITRGM TNQSDTDNFP DSKDSPGDVQ RSKLSPVLDG VSELRHSFDG SAADRYLLSQ SSQPQSAATA PSAMFPYPGQ HGPAHPAFSI GSPSRYMAHH PVITNGAYNS LLSNSSPQGY PTAGYPYPQQ YGHSYQGAPF YQFSSTQ (1-196 aa encoded by BC104844)
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: T-box brain gene 1; T-box brain protein 1; T-box, brain, 1; T-box, brain, 1-like; T-brain-1; TBR-1; TES-56
Gene Aliases: TBR-1; TBR1; TES-56
UniProt ID: (Human) Q16650, (Mouse) Q64336
Entrez Gene ID: (Human) 10716, (Mouse) 21375, (Rat) 680427
Molecular Function:
Rel homology transcription factor
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