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Proteintech
TBR1 Polyclonal Antibody
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Product Details
20932-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TBR1 Fusion Protein Ag14935 (1-196 aa encoded by BC104844)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQLEHCLSP SIMLSKKFLN VSSSYPHSGG SELVLHDHPI ISTTDNLERS SPLKKITRGM TNQSDTDNFP DSKDSPGDVQ RSKLSPVLDG VSELRHSFDG SAADRYLLSQ SSQPQSAATA PSAMFPYPGQ HGPAHPAFSI GSPSRYMAHH PVITNGAYNS LLSNSSPQGY PTAGYPYPQQ YGHSYQGAPF YQFSSTQ (1-196 aa encoded by BC104844)
Target Information
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: T-box brain gene 1; T-box brain protein 1; T-box, brain, 1; T-box, brain, 1-like; T-brain-1; TBR-1; TES-56
Gene Aliases: TBR-1; TBR1; TES-56
UniProt ID: (Human) Q16650, (Mouse) Q64336
Entrez Gene ID: (Human) 10716, (Mouse) 21375, (Rat) 680427
conditioned taste aversion
transcription, DNA-templated
brain development
specification of organ identity
amygdala development
commitment of neuronal cell to specific neuron type in forebrain
hindbrain development
positive regulation of transcription from RNA polymerase II promoter
regulation of axon guidance
regulation of transcription, DNA-templated
regulation of gene expression
regulation of neuron projection development
neuron differentiation
axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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