Immunogen sequence: VITQGQYSFLV VPCTGTNSFG SPAAQTCLNE Y
Highest antigen sequence identity to the following orthologs - mouse 78%, rat 69%.
TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
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Protein Aliases: FLJ10407; FLJ12556; FLJ34120; hNDC1; nuclear division cycle 1 homolog; Nucleoporin NDC1; RP4-654H19.1; Transmembrane protein 48
Gene Aliases: NDC1; NET3; TMEM48
UniProt ID: (Human) Q9BTX1
Entrez Gene ID: (Human) 55706