TMEM48 is a component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. TMEM48 is required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane.
FLJ10407; FLJ12556; FLJ34120; hNDC1; nuclear division cycle 1 homolog; Nucleoporin NDC1; RP4-654H19.1; Transmembrane protein 48
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