Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
16540-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TOP1MT Fusion Protein Ag9857 (253-601 aa encoded by BC052285)
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TESIQNSIK YIMLNPCSKL KGETAWQKFE TARRLRGFVD EIRSQYRADW KSREMKTRQR AVALYFIDKL ALRAGNEKED GEAADTVGCC SLRVEHVQLH PEADGCQHVV EFDFLGKDCI RYYNRVPVEK PVYKNLQLFM ENKDPRDDLF DRLTTTSLNK HLQELMDGLT AKVFRTYNAS ITLQEQLRAL TRAEDSIAAK ILSYNRANRV VAILCNHQRA TPSTFEKSMQ NLQTKIQAKK EQVAEARAEL RRARAEHKAQ GDGKSRSVLE KKRRLLEKLQ EQLAQLSVQA TDKEENKQVA LGTSKLNYLD PRISIAWCKR FRVPVEKIYS KTQRERFAWA LAMAGEDFEF (253-601 aa encoded by BC052285)
Target Information
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA topoisomerase I, mitochondrial; mitochondrial topoisomerase IB; TOP1M; TOP1mt; Topoisomerase I mitochondrial; Type IB Topoisomerase
Gene Aliases: TOP1MT
UniProt ID: (Human) Q969P6
Entrez Gene ID: (Human) 116447
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support