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Proteintech
TRPC1 Polyclonal Antibody
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Product Details
24727-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TRPC1 fusion protein Ag16488
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MMAALYPSTD LSGASSSSLP SSPSSSSPNE VMALKDVREV KEENTLNEKL FLLACDKGDY YMVKKILEEN SSGDLNINCV DVLGRNAVTI TIENENLDIL QLLLDYGCQK LMERIQNPEY STTMDVAPVI LAAHRNNYEI LTMLLKQDVS LPKPHAVGCE CTLCSAKNKK DSLRHSRFRL DIYRCLASPA LIMLTEEDPI LRAFELSADL KELSLVEVEF RNDYEELARQ CKMFAKDLLA QARNSRELEV ILNHTSSDEP LDKRGLLEER MNLSRLKLAI KYNQKEFVSQ SNCQQFLNTV WFGQMSGYRR KPTCKKIMTV LTVGIFWPVL SLCYLIAPKS QFGRIIHTP
Target Information
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: capacitative calcium channel protein Trp1; Short transient receptor potential channel 1; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; Transient receptor protein 1; TRP-1; Trp-related protein 1; TrpC1
Gene Aliases: HTRP-1; Mtrp1; TRP1; TRPC1; Trrp1
UniProt ID: (Human) P48995, (Mouse) Q61056, (Rat) Q9QX01
Entrez Gene ID: (Human) 7220, (Mouse) 22063, (Rat) 89821
calcium ion transport
manganese ion transport
melanin biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
response to calcium ion
calcium ion transmembrane transport
cellular response to hypoxia
regulation of cardiac conduction
transport
ion transport
saliva secretion
transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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