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Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
3010009O07Rik; AI115608; capacitative calcium channel protein Trp1; capacitative calcium entry channel; HTRP-1; membe; Mtrp1; mTrp2; Short transient receptor potential channel 1; smTRPC2; transient receptor potential canonical 1; transient receptor potential cation channel subfamily C member 1; transient receptor potential cation channel, subfamily C, member 1; transient receptor potential cation channel, subfamily C, member 1 L homeolog; transient receptor potential protein; transient receptor protein 1; trp; TRP1; TRP-1; TRP-1 protein; trp2; trpc1; trpc1.L; TRPC2a; TRPC2b; trp-related protein 1; Trrp1; Trrp2; XELAEV_18027727mg; xtrpc1
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