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Product Details
OSR00085W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide human TRPC1 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat, mouse, bovine, rabbit and chicken TRPC1.
Specificity of this antibody: TRPC1.
Target Information
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3010009O07Rik; AI115608; capacitative calcium channel protein Trp1; membe; mTrp2; Short transient receptor potential channel 1; smTRPC2; transient receptor potential canonical 1; transient receptor potential cation channel, subfamily C, member 1; Transient receptor protein 1; TRP-1; TRP-1 protein; Trp-related protein 1; trp2; TrpC1; TRPC2a; TRPC2b; Trrp2
Gene Aliases: HTRP-1; Mtrp1; TRP1; TRPC1; Trrp1
UniProt ID: (Human) P48995, (Mouse) Q61056, (Rat) Q9QX01
Entrez Gene ID: (Human) 7220, (Mouse) 22063, (Rat) 89821
calcium ion transport
manganese ion transport
melanin biosynthetic process
positive regulation of release of sequestered calcium ion into cytosol
regulation of cytosolic calcium ion concentration
response to calcium ion
calcium ion transmembrane transport
cellular response to hypoxia
regulation of cardiac conduction
transport
ion transport
saliva secretion
transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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