Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Glycerol (1:1) may be added for additional stability.
Reconstitute in 100 µL of sterile water.
OSR00085W can be used with blocking peptide GST00014P.
The peptide is homologous in rat, mouse, bovine, rabbit and chicken TRPC1.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. Interacts with ITPR3. Appears to be ubiquitous.
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