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Invitrogen
Transferrin Polyclonal Antibody, FITC
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Product Details
PA1-86736
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Pure human transferrin prepared from pooled normal human serum
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Amount
1 mg
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA1-86736 shows minimal cross reactivity with related serum proteins.
Sheep anti Human transferrin antibody recognizes human transferrin, an approximately 80 kDa blood plasma glycoprotein synthesized by the liver, which contains two specific high affinity iron (Fe3+) binding sites and is responsible for the transport and supply of an exchangeable pool of iron, through binding to cell surface transferrin receptors.
Target Information
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; Serotransferrin; Siderophilin; transferin; Transferrin; transferrin precursor; unnamed protein product
Gene Aliases: HEL-S-71p; PRO1400; PRO1557; PRO2086; TF; TFQTL1
UniProt ID: (Human) P02787
Entrez Gene ID: (Human) 7018
ion transport
iron ion transport
cellular iron ion homeostasis
cell surface receptor signaling pathway
response to bacterium
antibacterial humoral response
osteoclast differentiation
regulation of protein stability
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of receptor-mediated endocytosis
multicellular organismal iron ion homeostasis
cellular response to iron ion
ferrous iron export
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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