MA5-17922 targets CD71/transferrin receptor in FACS applications and shows reactivity with Mouse samples.
The MA5-17922 immunogen is mouse CD71.
Cell surface transferrin receptor (CD71) is a disulfide-bonded homodimeric glycoprotein. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. Transferrin receptor (CD71) has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
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Protein Aliases: CD71; mammary tumor virus receptor 1; TFR; TFR1; TR; Transferrin receptor protein 1; TRFR
Gene Aliases: 2610028K12Rik; AI195355; AI426448; AU015758; CD71; E430033M20Rik; Mtvr-1; Mtvr1; p90; TFR; TFR1; Tfrc; TR; Trfr
UniProt ID: (Mouse) Q62351
Entrez Gene ID: (Mouse) 22042
Molecular Function: receptor