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Proteintech
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Immunogen sequence: MHAPGMKKI KLDTPEEIAR WREERRKNYP TLANIERKKK LKLEKEKRGA VLTTTQYGKM KGMSRHSQMA KIRSPGKNHK WKNDNSRQRA VTGSGSHLCD LKLEGPPEAN ADPLGVLINS DSESDKEEKP QHSVIPKEVT PALCSLMSSY GSLSGSESEP EETPIKTEAD VLAENQVLDS SAPKSPSQDV KATVRNFSEA KSENRKKSFE KTNPKRKKDY HNYQTLFEPR THHPYLLEML LAPDIRHERN VILQCVRYII KKDFFGLDTN SAKSKDV (1-276 aa encoded by BC017745)
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FMR1-interacting protein NUFIP1; Nuclear FMR1-interacting protein 1; Nuclear FMRP-interacting protein 1; NUFIP1, FMR1 interacting protein 1; RNA binding protein
Gene Aliases: bA540M5.1; NUFIP; NUFIP1; Rsa1
UniProt ID: (Human) Q9UHK0
Entrez Gene ID: (Human) 26747
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