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View additional product information for DTSSP (3,3'-dithiobis(sulfosuccinimidyl propionate)) - FAQs (21578)
2 product FAQs found
DTSSP (3,3'-dithiobis(sulfosuccinimidyl propionate)) is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended. Please see section 8.1 of our Terms & Conditions of Sale (https://www.thermofisher.com/content/dam/LifeTech/Documents/PDFs/Terms-and-Conditions-of-Sale.pdf) for more details.
Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.
A homobifunctional cross-linker has the same reactive group on both ends, for example two amine-reactive groups. It is used in a one-step conjugation where the two molecules are mixed prior to the addition of the cross-linker. This leads to less efficient cross-linking because polymers can easily be created. A heterobifunctional cross-linker has two different reactive groups, for example an amine-reactive group on one end and a sulhydryl reactive group on the other. These can be used in two-step conjugations by reacting the fIrst end with the molecule containing its reactive group, and then adding the molecule that is reactive towards the other end. This leads to much more efficient cross-linking because polymerization does not occur.
Find additional tips, troubleshooting help, and resources within our Protein Purification and Isolation Support Center.