Thermo Scientific™

Sulfo-GMBS (N-γ-maleimidobutyryl-oxysulfosuccinimide ester)

Catalog number:  22324

 Related applications:

Protein Labeling & Crosslinking

Error loading your content!

  Catalog number
Select a plan
Unit size
Price ({{currency}}) Availability Qty
{{product.sku}} {{product.sku}} also known as {{product.formattedSku}} 
Pro add-ons

Your on-site stock

›› {{supplyCenter.scName}}({{scProduct.stockOnHand}} In stock)
›› {{supplyCenter.scName}}(Out of stock)
›› {{supplyCenter.scName}}
This item is not currently available on-site. Depending on your Supply Center settings you may be able to add the item to cart above else use the Order Non-Stocked Items' tab on the Supply Center home page.
Back to top


Thermo Scientific Pierce Sulfo-GMBS is a water-soluble amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).

Features of Sulfo-GMBS:

Reactive groups: sulfo-NHS ester and maleimide
Reactive towards: amino and sulfhydryl groups
• Non-cleavable
• Water-soluble (compare to GMBS)
• Has a low potential for illiciting crosslinker immune response, ensuring that the primary response to the antigen-carrier protein conjugate is not diluted by a response against a determinant on the crosslinker
• GMBS and Sulfo-GMBS are reported to be less immunogenic than SMCC

Product References:

Crosslinker Application Guide -- search for recent literature references for this product

Related Products
GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)
For Research Use Only. Not for use in diagnostic procedures.


Crosslinker Type: Heterobifunctional
Labeling Method: Chemical Labeling
Product Line: Pierce™
Product Size: 50 mg
Solubility: Water
Spacer: Short

Contents & storage

Upon receipt store desiccated at -20° C. Product is shipped at ambient temperature.


Manuals & protocols