Thermo Scientific™

NHS-PEG4-Azide

Catalog number: 26130
Thermo Scientific™

NHS-PEG4-Azide

Catalog number: 26130
Catalog Number
26130
Unit Size
100 mg
Price (USD)
Price: 371.00
Online price: 350.65
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
26130100 mg
Price: 371.00
Online price: 350.65
Your price:
-
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Thermo Scientific NHS-PEG4-Azide is an amine-reactive compound that can be used to derivatize primary amines of proteins or amine-coated polymer surfaces for ligation to phosphine-modified molecules.

This NHS-ester compound reacts to form covalent bonds with primary amines (e.g., side chain of lysine residues or aminosilane-coated surfaces). The azide (N3) group reacts with phosphine-labeled molecules by a mechanism known as Staudinger chemistry, enabling efficient and specific conjugation of derivatized molecules in biological samples.

Features of NHS-PEG4-Azide:

Soluble—reagent easily dissolves in water-miscible solvents for subsequent dilution in aqueous reaction mixtures with cell lysates and other biological samples
Compatible—reaction chemistry occurs effectively in simple buffer conditions; requires no accessory reagents such as copper or reducing agents
Specific—NHS esters are specific for covalent attachment to primary amines (side chain of lysine or N-terminus of polypeptides)
Chemoselective—azide and phosphine groups do not react or interfere with components of biological samples (bioorthogonal) but conjugate to one another with high efficiency

Related Products
NHS-Azide
NHS-Phosphine
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Amine-Phosphine
Cleavable
No
Description
NHS-PEG4-Azide
Molecular Weight (g/mol)
388.37
PEGylated
Yes
Spacer Arm Length
18.9 Å
Cell Permeability
Not determined
Shipping Condition
Ambient
Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Heterobifunctional
Reactive Moiety
Amine, Azide, NHS Ester
Spacer
Medium (10 to 30 Å)
Form
Liquid
Quantity
100 mg
Solubility
DMF, DMSO
Format
Standard
Water Soluble
No
Product Type
Crosslinker

Contents & Storage

Upon receipt store at -20°C protected from light and moisture.

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